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human JPH3 shRNA silencing AAV

Name 
AAV-h-JPH3-shRNA
Cat No 
shAAV-212593
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human JPH3.

shAAV-212593
AAV-h-JPH3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human JPH3 (junctophilin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAGL237; HDL2; JP-3; JP3; TNRC22
Description (Vector)
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansions at the Huntington's disease (HD)-like 2 locus have been identified in this gene, which is a member of the junctophilin gene family.
Gene ID
57338
Gene Name (Vector)
junctophilin 3
Gene Symbol
JPH3
HGNC ID
HGNC:14203
ORF Size (aa)
2247
ORF Size (bp)
2247 bp
RefSeq ID
NM_020655
RefSeq Synonyms
NM_020655, NM_001271605, NM_001271604, BC036533,
Species
human
UniGene ID
Hs.592068

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.