human JAG1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human JAG1.
shAAV-212568
AAV-h-JAG1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human JAG1 (jagged 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGS; AHD; AWS; CD339; HJ1; JAGL1; MGC104644;
Description (Vector)
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Gene ID
182
Gene Name (Vector)
jagged 1
Gene Symbol
JAG1
ORF Size (aa)
3657
ORF Size (bp)
3657 bp
RefSeq ID
NM_000214
RefSeq Synonyms
NM_000214, BC126207, BC126205, BC098393,
Species
human
UniGene ID
Hs.714736
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.