human IZUMO1 shRNA silencing AAV

Name
AAV-h-IZUMO1-shRNA

Cat No
shAAV-212567

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human IZUMO1.

shAAV-212567

AAV-h-IZUMO1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IZUMO1 (izumo sperm-egg fusion 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IZUMO; OBF

Description (Vector)

The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 (PubMed 15759005)).(supplied by OMIM, Mar 2008)

Gene ID

284359

Gene Name (Vector)

izumo sperm-egg fusion 1

Gene Symbol

IZUMO1

HGNC ID

HGNC:28539

ORF Size (aa)

1053

RefSeq ID

NM_182575

RefSeq Synonyms

NM_182575, NM_001321865, NM_001321864, BC034769,

Species

human

UniGene ID

Hs.714990

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.