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human ITGB1BP1 shRNA silencing AAV

Name 
AAV-h-ITGB1BP1-shRNA
Cat No 
shAAV-212501
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ITGB1BP1.

shAAV-212501
AAV-h-ITGB1BP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ITGB1BP1 (integrin subunit beta 1 binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ICAP-1A; ICAP-1alpha; ICAP-1B; ICAP1; ICAP1A; ICAP1B
Description (Vector)
The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.
Gene ID
9270
Gene Name (Vector)
integrin subunit beta 1 binding protein 1
Gene Symbol
ITGB1BP1
HGNC ID
HGNC:23927
ORF Size (aa)
603
RefSeq ID
NM_004763
RefSeq Synonyms
NM_022334, NM_004763, NM_001319070, NM_001319069, NM_001319068, NM_001319067, NM_001319066, BC012264,
Species
human
UniGene ID
Hs.467662

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.