human ITGA7 shRNA silencing AAV

Name
AAV-h-ITGA7-shRNA

Cat No
shAAV-212485

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ITGA7.

shAAV-212485

AAV-h-ITGA7-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ITGA7 (integrin subunit alpha 7). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

ITGA7 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene ID

3679

Gene Name (Vector)

integrin subunit alpha 7

Gene Symbol

ITGA7

HGNC ID

HGNC:6143

ORF Size (aa)

3414

ORF Size (bp)

3414 bp

RefSeq ID

NM_002206

RefSeq Synonyms

NM_002206, NM_001144997, NM_001144996, BC050280,

Species

human

UniGene ID

Hs.524484

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.