human INTS5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human INTS5.
shAAV-212324
AAV-h-INTS5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human INTS5 (integrator complex subunit 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
INT5; integrator complex subunit 5; KIAA1698
Description (eCommerce)
INT5 has been identified as a component of the twelve-subunit integrator complex that functions in RNA Pol II mediated 3’-end mRNA processing of the U1 and U2 small nuclear RNAs (snRNAs).
Description (Vector)
INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)
Gene ID
80789
Gene Name (eCommerce)
integrator complex subunit 5
Gene Name (Vector)
integrator complex subunit 5
Gene Symbol
INTS5
HGNC ID
HGNC:29352
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3060
ORF Size (bp)
3060 bp
Protein Name (eCommerce)
Integrator complex subunit 5
RefSeq ID
NM_030628
RefSeq Synonyms
NM_030628, BC060841,
Research Areas
RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
INT5 has been identified as a component of the twelve-subunit integrator complex that functions in RNA Pol II mediated 3’-end mRNA processing of the U1 and U2 small nuclear RNAs (snRNAs).
UniGene ID
Hs.458390
UniProt ID (eCommerce)
Q6P9B9
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.