human INPP5K shRNA silencing AAV

Name
AAV-h-INPP5K-shRNA

Cat No
shAAV-212296

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human INPP5K.

shAAV-212296

AAV-h-INPP5K-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human INPP5K (inositol polyphosphate-5-phosphatase K). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PPS; SKIP

Description (Vector)

INPP5K encodes a protein with 5-phosphatase activity toward polyphosphate inositol. The protein localizes to the cytosol in regions lacking actin stress fibers. It is thought that this protein may negatively regulate the actin cytoskeleton. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

51763

Gene Name (Vector)

inositol polyphosphate-5-phosphatase K

Gene Symbol

INPP5K

HGNC ID

HGNC:33882

ORF Size (aa)

1347

ORF Size (bp)

1347 bp

RefSeq ID

NM_016532

RefSeq Synonyms

NM_130766, NM_016532, NM_001135642, BC004362,

Species

human

UniGene ID

Hs.632238

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.