human IMMT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IMMT.
shAAV-212232
AAV-h-IMMT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IMMT (inner membrane mitochondrial protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; heart muscle protein; HMP; Mic60; MICOS complex subunit MIC60; MINOS2; mitochondrial inner membrane organizing system 2; mitochondrial inner membrane protein; mitofilin; motor protein; P87; P87/89; P89; PIG4; PIG52; proliferation-inducing gene 4
Description (eCommerce)
Mitofilin is a component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Mitofilin plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology [taken from NCBI Entrez Gene (Gene ID: 10989)].
Gene ID
10989
Gene Name (eCommerce)
inner membrane mitochondrial protein
Gene Name (Vector)
inner membrane mitochondrial protein
Gene Symbol
IMMT
HGNC ID
HGNC:6047
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2277
ORF Size (bp)
2277 bp
Protein Name (eCommerce)
MICOS complex subunit MIC60
RefSeq ID
NM_006839
RefSeq Synonyms
NM_006839, NM_001100170, NM_001100169, BC002412,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Mitofilin is a component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Mitofilin plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology [taken from NCBI Entrez Gene (Gene ID: 10989)].
UniGene ID
Hs.148559
UniProt ID (eCommerce)
Q16891
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.