human IL27RA shRNA silencing AAV

Name 
AAV-h-IL27RA-shRNA
Cat No 
shAAV-212164
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IL27RA.

shAAV-212164
AAV-h-IL27RA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL27RA (interleukin 27 receptor subunit alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CRL1; IL-27RA; IL27R; TCCR; WSX1; zcytor1
Description (Vector)
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
Gene ID
9466
Gene Name (Vector)
interleukin 27 receptor subunit alpha
Gene Symbol
IL27RA
HGNC ID
HGNC:17290
ORF Size (aa)
1911
ORF Size (bp)
1911 bp
RefSeq ID
NM_004843
RefSeq Synonyms
NM_004843, BC028003,
Species
human
UniGene ID
Hs.132781

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.