human IL21 shRNA silencing AAV

Cat. No: shAAV-212139

Availability: 6-8 weeks

Name: AAV-h-IL21-shRNA

This is an AAV expressing shRNA for silencing of Human IL21.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IL21
Gene Name: interleukin 21
Gene ID: 59067
Gene Synonyms: CVID11; IL-21; Za11
ORF Size: 489 bp
RefSeq#: NM_021803
Gene Description: IL21 encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
UniGene ID: Hs.567559
HGNC ID: HGNC:6005