human IL1F7 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-212097
Availability:
6-8 weeks
Name:
AAV-h-IL1F7-shRNA
This is an AAV expressing shRNA for silencing of Human IL37.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- IL37
- Gene Name
- interleukin 37
- Gene ID
- 27178
- Gene Synonyms
- FIL1; FIL1(ZETA); FIL1Z; IL-1F7; IL-1H; IL-1H4; IL-1RP1; IL-37; IL1F7; IL1H4; IL1RP1
- ORF Size
- 657 bp
- RefSeq#
- NM_173204
- Gene Description
- IL37 is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
- UniGene ID
- Hs.166371
- HGNC ID
- HGNC:15563
Related Products
Product | Cat No. |
---|---|
AAV-h-IL1F7 | AAV-212097 |
Ad-h-IL1F7 | ADV-212097 |
Ad-h-IL1F7-shRNA | shADV-212097 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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