human IL11 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IL11.
shAAV-212025
AAV-h-IL11-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IL11 (interleukin 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGIF; IL-11
Description (Vector)
IL11 is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Gene ID
3589
Gene Name (Vector)
interleukin 11
Gene Symbol
IL11
HGNC ID
HGNC:5966
ORF Size (aa)
600
RefSeq ID
NM_000641
RefSeq Synonyms
NM_001267718, NM_000641, BC012506,
Species
human
UniGene ID
Hs.467304
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.