human IL10RB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IL10RB.
shAAV-212024
AAV-h-IL10RB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IL10RB (interleukin 10 receptor subunit beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2
Description (Vector)
IL10RB belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.
Gene ID
3588
Gene Name (Vector)
interleukin 10 receptor subunit beta
Gene Symbol
IL10RB
HGNC ID
HGNC:5965
ORF Size (aa)
978
ORF Size (bp)
978 bp
RefSeq ID
NM_000628
RefSeq Synonyms
NM_000628, BC001903,
Species
human
UniGene ID
Hs.654593
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.