human IGLL1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IGLL1.
shAAV-211970
AAV-h-IGLL1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IGLL1 (immunoglobulin lambda like polypeptide 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
14.1; AGM2; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; VPREB2
Description (Vector)
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
3543
Gene Name (Vector)
immunoglobulin lambda like polypeptide 1
Gene Symbol
IGLL1
HGNC ID
HGNC:5870
ORF Size (aa)
642
RefSeq ID
NM_020070
RefSeq Synonyms
NM_152855, NM_020070, BC012293,
Species
human
UniGene ID
Hs.348935
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.