human IGFBP4 shRNA silencing AAV

Name
AAV-h-IGFBP4-shRNA

Cat No
shAAV-211933

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human IGFBP4.

shAAV-211933

AAV-h-IGFBP4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IGFBP4 (insulin like growth factor binding protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BP-4; HT29-IGFBP; IBP4; IGFBP-4

Description (Vector)

IGFBP4 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

Gene ID

3487

Gene Name (Vector)

insulin like growth factor binding protein 4

Gene Symbol

IGFBP4

HGNC ID

HGNC:5473

ORF Size (aa)

777

ORF Size (bp)

777 bp

RefSeq ID

NM_001552

RefSeq Synonyms

NM_001552, BC016041,

Species

human

UniGene ID

Hs.462998

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.