human IFT80 shRNA silencing AAV

Name
AAV-h-IFT80-shRNA

Cat No
shAAV-211899

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human IFT80.

shAAV-211899

AAV-h-IFT80-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IFT80 (intraflagellar transport 80). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ATD2; SRTD2; WDR56

Description (Vector)

IFT80 is part of the intraflagellar transport complex B and is necessary for the function of motile and sensory cilia. Defects in this gene are a cause of asphyxiating thoracic dystrophy 2 (ATD2). Three transcript variants encoding two different isoforms have been found for this gene.

Gene ID

57560

Gene Name (Vector)

intraflagellar transport 80

Gene Symbol

IFT80

HGNC ID

HGNC:29262

ORF Size (aa)

2334

ORF Size (bp)

2334 bp

RefSeq ID

NM_020800

RefSeq Synonyms

NM_020800, NM_001190242, NM_001190241, BC113669, BC101494,

Species

human

UniGene ID

Hs.478095

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.