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human IFRD1 shRNA silencing AAV

Name 
AAV-h-IFRD1-shRNA
Cat No 
shAAV-211884
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IFRD1.

shAAV-211884
AAV-h-IFRD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IFRD1 (interferon related developmental regulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PC4; TIS7
Description (Vector)
IFRD1 is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. IFRD1 may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants.
Gene ID
3475
Gene Name (Vector)
interferon related developmental regulator 1
Gene Symbol
IFRD1
HGNC ID
HGNC:5456
ORF Size (aa)
1356
ORF Size (bp)
1356 bp
RefSeq ID
NM_001550
RefSeq Synonyms
NM_001550, NM_001197080, NM_001197079, NM_001007245, BC001272,
Species
human
UniGene ID
Hs.7879

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.