human HVCN1 shRNA silencing AAV

Name
AAV-h-HVCN1-shRNA

Cat No
shAAV-211726

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human HVCN1.

shAAV-211726

AAV-h-HVCN1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HVCN1 (hydrogen voltage gated channel 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HV1; VSOP

Description (Vector)

HVCN1 encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

84329

Gene Name (Vector)

hydrogen voltage gated channel 1

Gene Symbol

HVCN1

HGNC ID

HGNC:28240

ORF Size (aa)

711

ORF Size (bp)

711 bp

RefSeq ID

NM_032369

RefSeq Synonyms

NM_032369, NM_001256413, NM_001040107, BC032672, BC009731, BC007277,

Species

human

UniGene ID

Hs.334637

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.