human HUS1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HUS1B.
shAAV-211722
AAV-h-HUS1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HUS1B (HUS1 checkpoint clamp component B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
HUS1B is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.
Gene ID
135458
Gene Name (Vector)
HUS1 checkpoint clamp component B
Gene Symbol
HUS1B
HGNC ID
HGNC:16485
ORF Size (aa)
837
ORF Size (bp)
837 bp
RefSeq ID
NM_148959
RefSeq Synonyms
NM_148959, BC101699, BC101697,
Species
human
UniGene ID
Hs.669039
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.