human HTR5A shRNA silencing AAV

Name
AAV-h-HTR5A-shRNA

Cat No
shAAV-211707

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HTR5A.

shAAV-211707

AAV-h-HTR5A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HTR5A (5-hydroxytryptamine receptor 5A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

5-HT5A

Description (Vector)

The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization.

Gene ID

3361

Gene Name (Vector)

5-hydroxytryptamine receptor 5A

Gene Symbol

HTR5A

HGNC ID

HGNC:5300

ORF Size (aa)

1074

RefSeq ID

NM_024012

RefSeq Synonyms

NM_024012, BC113468, BC112021,

Species

human

UniGene ID

Hs.65791

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.