human HTR3B shRNA silencing AAV

Name
AAV-h-HTR3B-shRNA

Cat No
shAAV-211698

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HTR3B.

shAAV-211698

AAV-h-HTR3B-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HTR3B (5-hydroxytryptamine receptor 3B). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

5-HT3B

Description (Vector)

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor.

Gene ID

9177

Gene Name (Vector)

5-hydroxytryptamine receptor 3B

Gene Symbol

HTR3B

HGNC ID

HGNC:5298

ORF Size (aa)

1323

ORF Size (bp)

1323 bp

RefSeq ID

NM_006028

RefSeq Synonyms

NM_006028, BC141515,

Species

human

UniGene ID

Hs.241377

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.