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human HTR3A shRNA silencing AAV

Name 
AAV-h-HTR3A-shRNA
Cat No 
shAAV-211696
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HTR3A.

shAAV-211696
AAV-h-HTR3A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HTR3A (5-hydroxytryptamine receptor 3A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3
Description (Vector)
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
3359
Gene Name (Vector)
5-hydroxytryptamine receptor 3A
Gene Symbol
HTR3A
HGNC ID
HGNC:5297
ORF Size (aa)
1437
ORF Size (bp)
1437 bp
RefSeq ID
NM_000869
RefSeq Synonyms
NM_213621, NM_001161772, NM_000869, BC004453, BC002354,
Species
human
UniGene ID
Hs.413899

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.