human HSPA9 shRNA silencing AAV

Name 
AAV-h-HSPA9-shRNA
Cat No 
shAAV-211648
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HSPA9.

shAAV-211648
AAV-h-HSPA9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HSPA9 (heat shock protein family A (Hsp70) member 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
75 kDa glucose-regulated protein; catecholamine-regulated protein 40; CRP40; CSA; epididymis secretory sperm binding protein Li 124m; EVPLS; GRP75; GRP-75; Heat shock 70 kDa protein 9; heat shock 70kD protein 9B; heat shock 70kDa protein 9 (mortalin); HEL-S-124m; HSPA9B; Mortalin; mortalin, perinuclear; mortalin2; mortalin-2; MOT; MOT2; MTHSP75; p66-mortalin; PBP74; peptide-binding protein 74; SAAN; SIDBA4; stress-70 protein, mitochondrial
Description (eCommerce)
HSPA9 a member of the heat shock protein 70 gene family. HSPA9 is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria taken from NCBI Entrez Gene (Gene ID: 3313)].
Description (Vector)
HSPA9 encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.
Gene ID
3313
Gene Name (eCommerce)
heat shock protein family A (Hsp70) member 9
Gene Name (Vector)
heat shock protein family A (Hsp70) member 9
Gene Symbol
HSPA9
HGNC ID
HGNC:5244
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2040
ORF Size (bp)
2040 bp
Protein Name (eCommerce)
Stress-70 protein, mitochondrial
RefSeq ID
NM_004134
RefSeq Synonyms
NM_004134, BC024034, BC000478,
Research Areas
Apoptosis,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Neurodegeneration,Parkinson's Disease,Parkin-Ubiquitin Proteasomal System,Protein Folding
Research Areas (Faceted)
cell_biology,metabolism,neurobiology
Species
human
Target Sentence
HSPA9 a member of the heat shock protein 70 gene family. HSPA9 is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria taken from NCBI Entrez Gene (Gene ID: 3313)].
UniGene ID
Hs.184233
UniProt ID (eCommerce)
P38646

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.