human HSPA1A shRNA silencing AAV

Name
AAV-h-HSPA1A-shRNA

Cat No
shAAV-211629

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HSPA1A.

shAAV-211629

AAV-h-HSPA1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HSPA1A (heat shock protein family A (Hsp70) member 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HEL-S-103; HSP70-1; HSP70-1A; HSP70.1; HSP70I; HSP72; HSPA1

Description (Vector)

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Gene ID

3303

Gene Name (Vector)

heat shock protein family A (Hsp70) member 1A

Gene Symbol

HSPA1A

HGNC ID

HGNC:5232

ORF Size (aa)

1926

ORF Size (bp)

1926 bp

RefSeq ID

NM_005345

RefSeq Synonyms

NM_005345, BC018740, BC009322, BC002453,

Species

human

UniGene ID

Hs.702139

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.