human HSP90B1 shRNA silencing AAV

Name 
AAV-h-HSP90B1-shRNA
Cat No 
shAAV-211620
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HSP90B1.

shAAV-211620
AAV-h-HSP90B1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HSP90B1 (heat shock protein 90 beta family member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ECGP; GP96; GRP94; HEL-S-125m; HEL35; TRA1
Description (Vector)
HSP90B1 encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.
Gene ID
7184
Gene Name (Vector)
heat shock protein 90 beta family member 1
Gene Symbol
HSP90B1
HGNC ID
HGNC:12028
ORF Size (aa)
2412
ORF Size (bp)
2412 bp
RefSeq ID
NM_003299
RefSeq Synonyms
NM_003299, BC066656,
Species
human
UniGene ID
Hs.192374

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.