human HSF4 shRNA silencing AAV

Name
AAV-h-HSF4-shRNA

Cat No
shAAV-211599

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HSF4.

shAAV-211599

AAV-h-HSF4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HSF4 (heat shock transcription factor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CTM; CTRCT5

Description (Vector)

Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

Gene ID

3299

Gene Name (Vector)

heat shock transcription factor 4

Gene Symbol

HSF4

HGNC ID

HGNC:5227

ORF Size (aa)

1386

ORF Size (bp)

1386 bp

RefSeq ID

NM_001538

RefSeq Synonyms

NM_001538, NM_001040667, BC153061, BC146446,

Species

human

UniGene ID

Hs.715679

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.