human HSD17B3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HSD17B3.
shAAV-211577
AAV-h-HSD17B3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EDH17B3; SDR12C2
Description (Vector)
This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
Gene ID
3293
Gene Name (Vector)
hydroxysteroid 17-beta dehydrogenase 3
Gene Symbol
HSD17B3
HGNC ID
HGNC:5212
ORF Size (aa)
933
RefSeq ID
NM_000197
RefSeq Synonyms
NM_000197, BC034281,
Species
human
UniGene ID
Hs.477
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.