human HRH3 shRNA silencing AAV

Name
AAV-h-HRH3-shRNA

Cat No
shAAV-211525

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HRH3.

shAAV-211525

AAV-h-HRH3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HRH3 (histamine receptor H3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GPCR97; HH3R

Description (Vector)

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

Gene ID

11255

Gene Name (Vector)

histamine receptor H3

Gene Symbol

HRH3

HGNC ID

HGNC:5184

ORF Size (aa)

1338

ORF Size (bp)

1338 bp

RefSeq ID

NM_007232

RefSeq Synonyms

NM_007232, BC096840,

Species

human

UniGene ID

Hs.251399

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.