human HOXD8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HOXD8.
shAAV-211482
AAV-h-HOXD8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HOXD8 (homeobox D8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HOX4; HOX4E; HOX5.4
Description (Vector)
HOXD8 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. HOXD8 is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. In addition to effects during embryogenesis, this particular gene may also play a role in adult urogenital tract function. Alternate splicing results in multiple transcript variants.
Gene ID
3234
Gene Name (Vector)
homeobox D8
Gene Symbol
HOXD8
HGNC ID
HGNC:5139
ORF Size (aa)
870
ORF Size (bp)
870 bp
RefSeq ID
NM_019558
RefSeq Synonyms
NM_019558, NM_001199747, NM_001199746, BC090853, BC038709,
Species
human
UniGene ID
Hs.700870
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.