human HOXA11 shRNA silencing AAV

Name
AAV-h-HOXA11-shRNA

Cat No
shAAV-211433

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human HOXA11.

shAAV-211433

AAV-h-HOXA11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HOXA11 (homeobox A11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HOX1; HOX1I; RUSAT1

Description (Vector)

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.

Gene ID

3207

Gene Name (Vector)

homeobox A11

Gene Symbol

HOXA11

HGNC ID

HGNC:5101

ORF Size (aa)

942

ORF Size (bp)

942 bp

RefSeq ID

NM_005523

RefSeq Synonyms

NM_005523, BC040948,

Species

human

UniGene ID

Hs.249171

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.