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human HNRNPA2B1 shRNA silencing AAV

Name 
AAV-h-HNRNPA2B1-shRNA
Cat No 
shAAV-211353
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HNRNPA2B1.

shAAV-211353
AAV-h-HNRNPA2B1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HNRNPA2; HNRNPB1; HNRPA2; HNRPA2B1; HNRPB1; IBMPFD2; RNPA2; SNRPB1
Description (Vector)
HNRNPA2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. HNRNPA2B1 has been described to generate two alternatively spliced transcript variants which encode different isoforms.
Gene ID
3181
Gene Name (Vector)
heterogeneous nuclear ribonucleoprotein A2/B1
Gene Symbol
HNRNPA2B1
HGNC ID
HGNC:5033
ORF Size (aa)
750
ORF Size (bp)
750 bp
RefSeq ID
NM_002137
RefSeq Synonyms
NM_031243, NM_002137, BC000506,
Species
human
UniGene ID
Hs.487774

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.