human HLA-DOA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HLA-DOA.
shAAV-211214
AAV-h-HLA-DOA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HLA-DOA (major histocompatibility complex, class II, DO alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HLA-DNA; HLA-DZA; HLADZ
Description (Vector)
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
Gene ID
3111
Gene Name (Vector)
major histocompatibility complex, class II, DO alpha
Gene Symbol
HLA-DOA
HGNC ID
HGNC:4936
ORF Size (aa)
753
ORF Size (bp)
753 bp
RefSeq ID
NM_002119
RefSeq Synonyms
NM_002119, BC013183,
Species
human
UniGene ID
Hs.631991
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.