human HIST1H2BA shRNA silencing AAV

Name 
AAV-h-HIST1H2BA-shRNA
Cat No 
shAAV-211089
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HIST1H2BA.

shAAV-211089
AAV-h-HIST1H2BA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HIST1H2BA (histone cluster 1 H2B family member a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
89
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA317E16.3; H2BFU; STBP; TH2B; TSH2B; TSH2B.1
Description (Vector)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.
Gene ID
255626
Gene Name (Vector)
histone cluster 1 H2B family member a
Gene Symbol
HIST1H2BA
HGNC ID
HGNC:18730
ORF Size (aa)
384
RefSeq ID
NM_170610
RefSeq Synonyms
NM_170610, BC066242, BC066241, BC066240, BC066239, BC066238,
Species
human
UniGene ID
Hs.591786

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.