human HIST1H1T shRNA silencing AAV

Name
AAV-h-HIST1H1T-shRNA

Cat No
shAAV-211063

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HIST1H1T.

shAAV-211063

AAV-h-HIST1H1T-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HIST1H1T (histone cluster 1 H1 family member t). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

dJ221C16.2; H1.6; H1FT; H1t

Description (Vector)

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Gene ID

3010

Gene Name (Vector)

histone cluster 1 H1 family member t

Gene Symbol

HIST1H1T

HGNC ID

HGNC:4720

ORF Size (aa)

624

RefSeq ID

NM_005323

RefSeq Synonyms

NM_005323, BC130350, BC069517,

Species

human

UniGene ID

Hs.533293

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.