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human HIBCH shRNA silencing AAV

Name 
AAV-h-HIBCH-shRNA
Cat No 
shAAV-211016
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HIBCH.

shAAV-211016
AAV-h-HIBCH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HIBCH (3-hydroxyisobutyryl-CoA hydrolase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HIBYLCOAH
Description (Vector)
HIBCH encodes the enzyme responsible for hydrolysis of both HIBYL-CoA and beta-hydroxypropionyl-CoA. Mutations in this gene have been associated with 3-hyroxyisobutyryl-CoA hydrolase deficiency. Alternative splicing results in multiple transcript variants.
Gene ID
26275
Gene Name (Vector)
3-hydroxyisobutyryl-CoA hydrolase
Gene Symbol
HIBCH
HGNC ID
HGNC:4908
ORF Size (aa)
1161
ORF Size (bp)
1161 bp
RefSeq ID
NM_014362
RefSeq Synonyms
NM_198047, NM_014362, BC067822, BC005190,
Species
human
UniGene ID
Hs.656685

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.