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human HEYL shRNA silencing AAV

Name 
AAV-h-HEYL-shRNA
Cat No 
shAAV-210989
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HEYL.

shAAV-210989
AAV-h-HEYL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HEYL (hes related family bHLH transcription factor with YRPW motif-like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHb33; HESR3; HEY3; HRT3
Description (Vector)
HEYL encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Gene ID
26508
Gene Name (Vector)
hes related family bHLH transcription factor with YRPW motif-like
Gene Symbol
HEYL
HGNC ID
HGNC:4882
ORF Size (aa)
987
ORF Size (bp)
987 bp
RefSeq ID
NM_014571
RefSeq Synonyms
NM_014571, BC006087,
Species
human
UniGene ID
Hs.472566

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.