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human HES6 shRNA silencing AAV

Name 
AAV-h-HES6-shRNA
Cat No 
shAAV-210973
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HES6.

shAAV-210973
AAV-h-HES6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HES6 (hes family bHLH transcription factor 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHb41; bHLHc23; C-HAIRY1; HES-6
Description (Vector)
HES6 encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
55502
Gene Name (Vector)
hes family bHLH transcription factor 6
Gene Symbol
HES6
HGNC ID
HGNC:18254
ORF Size (aa)
675
ORF Size (bp)
675 bp
RefSeq ID
NM_018645
RefSeq Synonyms
NM_018645, NM_001282434, NM_001142853, BC007939,
Species
human
UniGene ID
Hs.42949

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.