human HERC6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HERC6.
shAAV-210955
AAV-h-HERC6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HERC6 (HECT and RLD domain containing E3 ubiquitin protein ligase family member 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 (PubMed 15676274)).(supplied by OMIM, Mar 2008)
Gene ID
55008
Gene Name (Vector)
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
Gene Symbol
HERC6
HGNC ID
HGNC:26072
ORF Size (aa)
3069
ORF Size (bp)
3069 bp
RefSeq ID
NM_017912
RefSeq Synonyms
NM_017912, NM_001165136, BC042047, BC035775,
Species
human
UniGene ID
Hs.529317
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.