human HEPH shRNA silencing AAV

Name
AAV-h-HEPH-shRNA

Cat No
shAAV-210949

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HEPH.

shAAV-210949

AAV-h-HEPH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HEPH (hephaestin). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CPL

Description (Vector)

HEPH is similar to an iron transport protein found in mouse. The mouse protein is similar to ceruloplasmin, a serum multi-copper ferroxidase, and is thought to be a membrane-bound protein responsible for transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system. In mouse, defects in this gene can lead to severe microcytic anemia. Three transcript variants encoding different isoforms have been described for this gene.

Gene ID

9843

Gene Name (Vector)

hephaestin

Gene Symbol

HEPH

HGNC ID

HGNC:4866

ORF Size (aa)

3477

ORF Size (bp)

3477 bp

RefSeq ID

NM_014799

RefSeq Synonyms

NM_138737, NM_014799, NM_001282141, NM_001130860, BC011561,

Species

human

UniGene ID

Hs.31720

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.