human HELZ shRNA silencing AAV

Name
AAV-h-HELZ-shRNA

Cat No
shAAV-210943

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human HELZ.

shAAV-210943

AAV-h-HELZ-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HELZ (helicase with zinc finger). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DHRC; DRHC; HUMORF5

Description (Vector)

HELZ is a member of the superfamily I class of RNA helicases. RNA helicases alter the conformation of RNA by unwinding double-stranded regions, thereby altering the biologic activity of the RNA molecule and regulating access to other proteins (Wagner et al., 1999 (PubMed 10471385)).(supplied by OMIM, Mar 2008)

Gene ID

9931

Gene Name (Vector)

helicase with zinc finger

Gene Symbol

HELZ

HGNC ID

HGNC:16878

ORF Size (aa)

5829

ORF Size (bp)

5829 bp

RefSeq ID

NM_014877

RefSeq Synonyms

NM_014877, NM_001330447, BC144083, BC130582, BC094881,

Species

human

UniGene ID

Hs.569824

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.