human HECTD1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HECTD1.
shAAV-210927
AAV-h-HECTD1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HECTD1 (HECT domain E3 ubiquitin protein ligase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E3 ligase for inhibin receptor; E3 ubiquitin-protein ligase HECTD1; EULIR; HECT domain containing E3 ubiquitin protein ligase 1; HECT domain-containing protein 1; HECT-type E3 ubiquitin transferase HECTD1
Description (eCommerce)
HECT domain-containing protein 1 (HECTD1) is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. HECTD1 may be required for development of the head mesenchyme and neural tube closure [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9ULT8].
Gene ID
25831
Gene Name (eCommerce)
HECT domain E3 ubiquitin protein ligase 1
Gene Name (Vector)
HECT domain E3 ubiquitin protein ligase 1
Gene Symbol
HECTD1
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
7833
ORF Size (bp)
7833 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase HECTD1
RefSeq ID
NM_015382
RefSeq Synonyms
NM_015382, BC172391,
Research Areas
Neurobiology,Neurodevelopment,Ubiquitination
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology
Species
human
Target Sentence
HECT domain-containing protein 1 (HECTD1) is a probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. HECTD1 may be required for development of the head mesenchyme and neural tube closure [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9ULT8].
UniGene ID
Hs.708017
UniProt ID (eCommerce)
Q9ULT8
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.