human HCLS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HCLS1.
shAAV-210868
AAV-h-HCLS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HCLS1 (hematopoietic cell-specific Lyn substrate 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CTTNL; Hematopoietic cell-specific LYN substrate 1; hematopoietic lineage cell-specific protein; HS1; lckBP1; p75
Description (eCommerce)
Hematopoietic lineage cell-specific protein (HS1) is a substrate of the antigen receptor-coupled tyrosine kinase. HS1 plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. HS1 may also be involved in the regulation of gene expression [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P14317].
Gene ID
3059
Gene Name (eCommerce)
hematopoietic cell-specific Lyn substrate 1
Gene Name (Vector)
hematopoietic cell-specific Lyn substrate 1
Gene Symbol
HCLS1
HGNC ID
HGNC:4844
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1461
ORF Size (bp)
1461 bp
Protein Name (eCommerce)
Hematopoietic lineage cell-specific protein
RefSeq ID
NM_005335
RefSeq Synonyms
NM_005335, NM_001292041, BC016758,
Research Areas
B-cell Receptor Signaling,Cancer,Fc Receptor Signaling,Immunology,Interleukin Signaling,Mitochondrion,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
cancer,cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
Hematopoietic lineage cell-specific protein (HS1) is a substrate of the antigen receptor-coupled tyrosine kinase. HS1 plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. HS1 may also be involved in the regulation of gene expression [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P14317].
UniGene ID
Hs.14601
UniProt ID (eCommerce)
P14317
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.