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human HAO1 shRNA silencing AAV

Name 
AAV-h-HAO1-shRNA
Cat No 
shAAV-210775
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human HAO1.

shAAV-210775
AAV-h-HAO1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HAO1 (hydroxyacid oxidase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GOX; GOX1; HAOX1
Description (Vector)
HAO1 is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
Gene ID
54363
Gene Name (Vector)
hydroxyacid oxidase 1
Gene Symbol
HAO1
HGNC ID
HGNC:4809
ORF Size (aa)
1113
ORF Size (bp)
1113 bp
RefSeq ID
NM_017545
RefSeq Synonyms
NM_017545, BC113667, BC113665,
Species
human
UniGene ID
Hs.193640

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.