human HABP2 shRNA silencing AAV

Name
AAV-h-HABP2-shRNA

Cat No
shAAV-210756

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HABP2.

shAAV-210756

AAV-h-HABP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HABP2 (hyaluronan binding protein 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FSAP; HABP; HGFAL; NMTC5; PHBP

Description (Vector)

HABP2 is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

3026

Gene Name (Vector)

hyaluronan binding protein 2

Gene Symbol

HABP2

HGNC ID

HGNC:4798

ORF Size (aa)

1683

ORF Size (bp)

1683 bp

RefSeq ID

NM_004132

RefSeq Synonyms

NM_004132, NM_001177660, BC031412,

Species

human

UniGene ID

Hs.422542

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.