human GZMA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GZMA.
shAAV-210717
AAV-h-GZMA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GZMA (granzyme A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CTLA3; HFSP
Description (Vector)
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
Gene ID
3001
Gene Name (Vector)
granzyme A
Gene Symbol
GZMA
HGNC ID
HGNC:4708
ORF Size (aa)
789
ORF Size (bp)
789 bp
RefSeq ID
NM_006144
RefSeq Synonyms
NM_006144, BC015739,
Species
human
UniGene ID
Hs.90708
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.