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human GYS2 shRNA silencing AAV

Name 
AAV-h-GYS2-shRNA
Cat No 
shAAV-210715
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GYS2.

shAAV-210715
AAV-h-GYS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GYS2 (glycogen synthase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
GYS2, liver glycogen synthase, catalyzes the rate-limiting step in the synthesis of glycogen - the transfer of a glucose molecule from UDP-glucose to a terminal branch of the glycogen molecule. Mutations in this gene cause glycogen storage disease type 0 (GSD-0) - a rare type of early childhood fasting hypoglycemia with decreased liver glycogen content.
Gene ID
2998
Gene Name (Vector)
glycogen synthase 2
Gene Symbol
GYS2
HGNC ID
HGNC:4707
ORF Size (aa)
2112
ORF Size (bp)
2112 bp
RefSeq ID
NM_021957
RefSeq Synonyms
NM_021957, BC126312, BC126310,
Species
human
UniGene ID
Hs.82614

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.