human GUK1 shRNA silencing AAV

Name
AAV-h-GUK1-shRNA

Cat No
shAAV-210695

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human GUK1.

shAAV-210695

AAV-h-GUK1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GUK1 (guanylate kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GMK

Description (Vector)

GUK1 is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene.

Gene ID

2987

Gene Name (Vector)

guanylate kinase 1

Gene Symbol

GUK1

HGNC ID

HGNC:4693

ORF Size (aa)

594

RefSeq ID

NM_000858

RefSeq Synonyms

NM_001242840, NM_001242839, NM_001159391, NM_001159390, NM_000858, BC091480, BC009914, BC006249,

Species

human

UniGene ID

Hs.376933

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.