human GUCY1A2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GUCY1A2.
shAAV-210686
AAV-h-GUCY1A2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GUCY1A2 (guanylate cyclase 1 soluble subunit alpha 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GC-SA2; GUC1A2
Description (Vector)
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
2977
Gene Name (Vector)
guanylate cyclase 1 soluble subunit alpha 2
Gene Symbol
GUCY1A2
HGNC ID
HGNC:4684
ORF Size (aa)
2199
ORF Size (bp)
2199 bp
RefSeq ID
NM_000855
RefSeq Synonyms
NM_001256424, NM_000855, BC144033, BC130488, BC130484,
Species
human
UniGene ID
Hs.654555
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.