human GTF3C5 shRNA silencing AAV

Name 
AAV-h-GTF3C5-shRNA
Cat No 
shAAV-210659
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human GTF3C5.

shAAV-210659
AAV-h-GTF3C5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human GTF3C5 (general transcription factor IIIC subunit 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
general transcription factor 3C polypeptide 5; general transcription factor IIIC, polypeptide 5, 63kDa; TF3C-epsilon; TFIIIC 63 kDa subunit; TFiiiC2-63; TFIIIC63; TFIIICepsilon; transcription factor IIIC 63 kDa subunit; transcription factor IIIC subunit epsilon; transcription factor IIIC, 63 kD
Description (eCommerce)
General transcription factor 3C polypeptide 5 (GTF3C5/TFIIIC63) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C5/TFIIIC63 interacts with TFIIIB and may facilitate TFIIIB and RNA polymerase III recruitment in association with TFIIIC102, TFIIIB90, and RPC62.
Gene ID
9328
Gene Name (eCommerce)
general transcription factor IIIC subunit 5
Gene Name (Vector)
general transcription factor IIIC subunit 5
Gene Symbol
GTF3C5
HGNC ID
HGNC:4668
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1560
ORF Size (bp)
1560 bp
Protein Name (eCommerce)
General transcription factor 3C polypeptide 5
RefSeq ID
NM_012087
RefSeq Synonyms
NM_012087, NM_001286709, NM_001122823, BC017337, BC011355,
Research Areas
Gene Expression,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
General transcription factor 3C polypeptide 5 (GTF3C5/TFIIIC63) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C5/TFIIIC63 interacts with TFIIIB and may facilitate TFIIIB and RNA polymerase III recruitment in association with TFIIIC102, TFIIIB90, and RPC62.
UniGene ID
Hs.495417
UniProt ID (eCommerce)
Q9Y5Q8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.