human GRIPAP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human GRIPAP1.
shAAV-210535
AAV-h-GRIPAP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human GRIPAP1 (GRIP1 associated protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GRASP-1; GRIP1-associated protein 1
Description (eCommerce)
GRIP1-associated protein 1 (GRASP-1) is a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). GRASP-1 interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function [taken from NCBI Entrez Gene (Gene ID: 56850)].
Description (Vector)
GRIPAP1 encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). In brain studies, the encoded protein was found with the GRIP/AMPA receptor complex. Multiple alternatively spliced transcript variants have been described that encode different protein isoforms; however, the full-length nature and biological validity of all of these variants have not been determined.
Gene ID
56850
Gene Name (eCommerce)
GRIP1 associated protein 1
Gene Name (Vector)
GRIP1 associated protein 1
Gene Symbol
GRIPAP1
HGNC ID
HGNC:18706
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2526
ORF Size (bp)
2526 bp
Protein Name (eCommerce)
GRIP1-associated protein 1
RefSeq ID
NM_020137
RefSeq Synonyms
NM_207672, NM_020137, BC101546, BC101544,
Research Areas
Cell Biology
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
GRIP1-associated protein 1 (GRASP-1) is a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). GRASP-1 interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA receptor function [taken from NCBI Entrez Gene (Gene ID: 56850)].
UniGene ID
Hs.109929
UniProt ID (eCommerce)
Q4V328
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.